Vanadium and Melanoma: A Systematic Review

The application of metals in biological systems has been a rapidly growing branch science. Vanadium investigated and reported as an anticancer agent. Melanoma is the most aggressive type skin cancer, incidence which increasing annually worldwide. It paramount importance to identify novel pharmacological agents for melanoma treatment. Herein, systematic review publications including “Melanoma Vanadium” was performed. Nine vanadium articles several cells lines such human A375, CN-mel murine B16F10, well vivo studies, are described. Vanadium-based compounds with activity against include: (1) oxidovanadium(IV); (2) XMenes; (3) pentoxide, (4) oxidovanadium(IV) pyridinonate compounds; (5) vanadate; (6) polysaccharides vanadium(IV/V) complexes; (7) mixed-metal binuclear ruthenium(II)–vanadium(IV) (8) pyridoxal-based complexes (9) functionalized nanoparticles yttrium vanadate doped europium. and/or materials show potential activities that may be used useful approach treat melanoma.